Letter 2269C is a general letter that usually indicates that the IRS has no return from you. Please see the Return Request Prep Steps.
Response to Letter 2269C
If you are able to copy your return, sign it in blue ink & send it by certified or overnight mail to the IRS at the address on the Letter 2269C. If you do not have the information or return prepared, call the IRS at 1-800-829-1040 to order your Wage & Income Transcripts for the tax year. This will give you the third-party documents which were registered with the IRS about you. Then, you can prepare any returns which need to be filed.
If you are confused or need attorney guidance contact Mr. Hopkins!